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| Recreate the major paradigm shift in molecular biology that started with a strand of DNA "The DNA Hypothesis" opens at a 1944 scientific conference at the Cold Spring Harbor Laboratory in New York where eminent biochemists and geneticists are to share the latest developments in the nascent field of molecular biology. Of critical interest are the claims of Oswald Avery who claims to have identified the active component of the "transforming principle," as DNA the genetic material that can change one strain of bacteria into another. But not all are in agreement; protein is the much likelier candidate as it has a complex structure that give it the required specificity. Students will try to answer the questions, What is the genetic carrier of information? What evidence is there for or against the proposed hypotheses of the molecular basis of heredity? And what criteria could be used to establish a candidate molecule as the carrier of genetic information? |
Details
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Using the Game Class Size & Scalability |
GAME MATERIALS
Reacting Consortium members can access all downloadable materials below. You will be asked to sign in before downloading.
Please Fill out the Permissions Request Form Before Using The DNA Hypothesis in Your Class!
Gamebook Students need a Gamebook, which includes directions, resources, and historical content. | Instructor's Manual The Instructor's Manual includes guidance for assigning roles, presenting historical context, assignments, activities and discussion topics, and more. | Role Sheets Students also need a Role Sheet, which contains biographical information, role-specific resources or assignments, and their character's secret victory objectives. |
Chad Curtis
Dr. Chad Curtis is a professor of data science and analytics at Nevada State University. He teaches courses in programming and statistics and mentors undergraduate researchers in biomedical research projects through the NIH-funded INBRE program. His research interests include nanoparticle therapeutics, machine learning, and the scholarship of teaching and learning. He has authored Reacting games for use in STEM classrooms including "Radioactive: The Chemists, the Anthropologists and the Advent of Radiocarbon Dating" and "The Cigarette Century: Tobacco and Cancer, 1964-1965." |
Jules Perna is a data science major at Nevada State University where she enjoys learning to code in Python and R. She has played multiple Reacting games including "The Cigarette Century" and "Cholera! at the Pump." She enjoys how games like "The DNA Hypothesis" can make biology and genetics more accessible to students.
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